The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 08, 2025

Filed:

Mar. 27, 2023
Applicants:

Board of Regents, the University of Texas System, Austin, TX (US);

The University of British Columbia, Vancouver, CA;

Inventors:

Marc Cox, El Paso, TX (US);

Artem Cherkasov, Vancouver, CA;

Fuqiang Ban, Vancouver, CA;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 249/08 (2006.01); A61K 31/4196 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07D 249/08 (2013.01); A61K 45/06 (2013.01); A61K 31/4196 (2013.01);
Abstract

Procedures for inhibiting hormone receptor activation include administering to a subject in need of hormone receptor inhibition a compound having a chemical structure of a molecule that, when docked in the PPIase pocket, could disrupt proline-rich loop conformation and interactions. Procedures for treating prostate cancer or breast cancer include administering to a subject having prostate cancer or breast cancer a compound having a chemical structure of a molecule that, when docked in the PPIase pocket, could disrupt proline-rich loop conformation and interactions.


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