The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 08, 2025
Filed:
Mar. 16, 2022
Abs Global, Inc., DeForest, WI (US);
David Appleyard, Madison, WI (US);
Daniel McAda, Madison, WI (US);
Zheng Xia, Middleton, WI (US);
James Maxwell Schiller, Madison, WI (US);
Frederick Savage, Austin, TX (US);
John Walker Rupel, Ii, Madison, WI (US);
Timothy Miller, Fitchburg, WI (US);
Alec Fisher, Madison, WI (US);
ABS Global, Inc., DeForest, WI (US);
Abstract
Disclosed is an approach to differentiating between different particle types in samples flowing through microfluidics chips. A sample may have an initial proportion of a first cell type to a second cell type. An illuminating light source may emit a coherent light at the sample, and light leaving the chip in a first direction may be detected using a first light detector, and light leaving the chip in a second direction (e.g., orthogonal to the first direction) may be detected using a second light detector. The detected light may be fluorescence. An orientational feature of a plurality of cells in the sample may be determined based on the light detected by the detectors. Based on the orientational features and the detected light, a biasing operation may be performed for each cell in the sample to obtain a modified proportion of cell types in the sample.