The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 08, 2025
Filed:
Nov. 08, 2019
Applicant:
Arbutus Biopharma Corporation, Burnaby, CA;
Inventors:
Michael J. Abrams, Custer, WA (US);
James Heyes, Vancouver, CA;
Richard J. Holland, Vancouver, CA;
Kieu Mong Lam, Richmond, CA;
Mark Wood, Port Moody, CA;
Assignee:
ARBUTUS BIOPHARMA CORPORATION, Vancouver, CA;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/51 (2006.01); A61K 31/713 (2006.01); C07F 7/18 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
A61K 9/5123 (2013.01); A61K 31/713 (2013.01); C07F 7/1804 (2013.01); C07F 7/1892 (2013.01); C12N 15/113 (2013.01); C12N 2310/14 (2013.01); C12N 2320/32 (2013.01);
Abstract
Certain embodiments of the invention provide a cationic lipid of formula (I): wherein R, R, Rand Rare defined as described herein, as well as methods of making these lipids. Certain embodiments of the invention also provide nucleic acid-lipid particles comprising a cationic lipid of formula (I), methods of making the lipid particles, and methods of delivering and/or administering the lipid particles.