The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 08, 2025

Filed:

Mar. 02, 2018
Applicant:

Duke University, Durham, NC (US);

Inventors:

Robert Morhard, Durham, NC (US);

Nirmala Ramanujam, Durham, NC (US);

David Katz, Raleigh, NC (US);

Assignee:

Duke University, Durham, NC (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/38 (2006.01); A61K 9/00 (2006.01); A61K 9/08 (2006.01); A61K 31/045 (2006.01); A61K 45/06 (2006.01); A61K 49/00 (2006.01); A61P 17/02 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
A61K 47/38 (2013.01); A61K 9/0019 (2013.01); A61K 9/08 (2013.01); A61K 31/045 (2013.01); A61K 45/06 (2013.01); A61K 49/0043 (2013.01); A61P 17/02 (2018.01); A61P 35/00 (2018.01);
Abstract

The present disclosure provides methods for the treatment of a lesion, such as a cancerous lesion, a precancerous lesion, or a benign lesion (e.g. a benign lesion on the skin) in a subject comprising administering to the subject a therapeutically effective amount of a therapy solution comprising a viscous carrier and an alcohol or hydrophobic anti-cancer agent, such that the lesion is treated. In some embodiments, the therapy solution includes an ethyl cellulose-ethanol mixture. In some embodiments, the therapy solution is administered to the lesion at a rate of from about 1 mL/hr to about 15 mL/hr.


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