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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12350325 B1

PDFFull Text
Date of Patent:
Jul. 08, 2025

Filed:

Jan. 24, 2020

Recombinant high growth rate influenza virus comprising mutations in m1, ns2, and pb2

Applicants:

Bluesky Immunotherapies Gmbh, Vienna, AT;

Vivaldi Biosciences Inc., Fort Collins, CO (US);

Inventors:

Thomas Muster, Vienna, AT;

Amy Aspelund, Fort Collins, CO (US);

Markus Wolschek, Vienna, AT;

Assignees:

VIVALDI BIOSCIENCES INC., Fort Collins, CO (US);

BLUESKY IMMUNOTHERAPIES GMBH, Vienna, AU;

Attorneys:

LOZA & LOZA, LLP

Michael Fedrick

Primary Examiner:

Jeffrey S Parkin

Int. Cl.
CPC ...
A61K 39/12 (2006.01); C12N 7/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/12 (2013.01); C12N 7/00 (2013.01); C12N 2760/16221 (2013.01); C12N 2760/16222 (2013.01); C12N 2760/16234 (2013.01); C12N 2760/16251 (2013.01);
Abstract

The present invention provides high growth influenza reassortant virus and high growth influenza reassortant virus vectors comprising amino acid modifications in the PB2, PB1, M1 and/or NS2 proteins which exhibit highly increased growth rates compared to unmodified influenza virus. Further provided are pharmaceutical compositions comprising reassortant virus and viral vectors comprising said modifications and their use for vaccination purposes.

Find Patent Forward Citations

Muster, Thomas. (2025). Recombinant high growth rate influenza virus comprising mutations in m1, ns2, and pb2 (U.S. Patent No. 12350325). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12350325

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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