The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 08, 2025

Filed:

Dec. 28, 2019
Applicant:

United Biomedical, Inc., Hauppauge, NY (US);

Inventors:

Chang Yi Wang, Cold Spring Harbor, NY (US);

Feng Lin, Hauppauge, NY (US);

Jiun Bo Chen, Taipei, TW;

Shuang Ding, Hauppauge, NY (US);

Assignee:

United Biomedical, Inc., Hauppauge, NY (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 39/008 (2006.01); A61P 29/00 (2006.01); C07K 16/24 (2006.01);
U.S. Cl.
CPC ...
A61K 39/008 (2013.01); A61K 39/00114 (2018.08); A61P 29/00 (2018.01); C07K 16/248 (2013.01); A61K 2039/505 (2013.01); A61K 2039/545 (2013.01); A61K 2039/55505 (2013.01); A61K 2039/55561 (2013.01); A61K 2039/55566 (2013.01); A61K 2039/6031 (2013.01); A61K 2039/627 (2013.01); A61K 2039/804 (2018.08); A61K 2039/884 (2018.08);
Abstract

The present disclosure is directed to individual peptide immunogen constructs targeting portions of the Interleukin-6 (IL-6) protein, compositions containing the constructs, antibodies elicited by the constructs, and methods for making and using the constructs and compositions thereof. The disclosed IL-6 peptide immunogen constructs contain a B cell epitope from IL-6 linked to a heterologous T helper cell (Th) epitope directly or through an optional heterologous spacer. The IL-6 peptide immunogen constructs stimulate the generation of highly specific antibodies directed to the IL-6 receptor (IL-6R) binding site for the prevention and/or treatment of diseases impacted by IL-6 dysregulation.


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