The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 08, 2025
Filed:
Aug. 15, 2019
Applicant:
Nantbio, Inc., Culver City, CA (US);
Inventor:
Patrick Soon-Shiong, Culver City, CA (US);
Assignee:
NantBio, Inc., Culver City, CA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/20 (2006.01); A61K 40/11 (2025.01); A61K 40/42 (2025.01); C12N 5/0783 (2010.01);
U.S. Cl.
CPC ...
A61K 38/20 (2013.01); A61K 38/2046 (2013.01); A61K 40/11 (2025.01); A61K 40/428 (2025.01); C12N 5/0636 (2013.01); C12N 2501/2307 (2013.01); C12N 2501/2315 (2013.01); C12N 2501/2321 (2013.01);
Abstract
Contemplated compositions and methods are directed to in vivo stimulation of Tcells to differentiate to Tcells in the presence of tumor cells expressing tumor associated antigens or tumor and patient specific neoepitopes using a pharmaceutical composition that includes an IL-15 portion and an IL-7 portion. The Tcells are then isolated and expanded in vitro, preferably using a pharmaceutical composition that includes an IL-15 portion, an IL-7 portion, and an IL21 portion, and subsequently administered to the patient.