The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 08, 2025

Filed:

Mar. 06, 2020
Applicant:

Niigata University, Niigata, JP;

Inventors:

Shuji Terai, Niigata, JP;

Atsunori Tsuchiya, Niigata, JP;

Suguru Takeuchi, Niigata, JP;

Assignee:

NIIGATA UNIVERSITY, Niigata, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/0786 (2010.01); A61K 35/28 (2015.01); A61P 1/16 (2006.01);
U.S. Cl.
CPC ...
A61K 35/28 (2013.01); A61P 1/16 (2018.01); C12N 5/0645 (2013.01);
Abstract

An induction method for a macrophage is provided, in which macrophages are cultured in the presence of exosomes produced from a mesenchymal stem cell to which interferon gamma has been added and are induced into anti-inflammatory macrophages. An anti-inflammatory macrophage-inducing agent includes exosomes produced from a mesenchymal stem cell to which interferon gamma has been added, as an active component. A pharmaceutical composition contains the inducing agent.


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