The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 08, 2025
Filed:
Feb. 25, 2020
Applicants:
Universitat DE Valencia-estudi General, Valencia, ES;
Elysium Health, Inc., New York, NY (US);
Inventors:
José María Estrela Arigüel, Valencia, ES;
Maria Elena Obrador Pla, Valencia, ES;
Rosario Salvador, Valencia, ES;
Ryan W. Dellinger, Azusa, CA (US);
Assignees:
UNIVERSITAT DE VALENCIA-ESTUDI GENERAL, Valencia, ES;
ELYSIUM HEALTH, INC., New York, NY (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/7076 (2006.01); A61K 31/05 (2006.01); A61K 31/437 (2006.01);
U.S. Cl.
CPC ...
A61K 31/7076 (2013.01); A61K 31/05 (2013.01); A61K 31/437 (2013.01);
Abstract
Provided herein are methods and compositions related to treating motor neuron diseases, such as ALS, in a subject by administering to the subject (e.g., orally administering to the subject) a composition comprising nicotinamide riboside, pterostilbene and a phosphodiesterase (PDE) inhibitor, including a PDE4 inhibitor such as ibudilast, and also including a thiol/cysteine donor, such as acetylcysteine.