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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12350260 B1

PDFFull Text
Date of Patent:
Jul. 08, 2025

Filed:

Apr. 05, 2020

Protease-activated receptor-2 inhibitors for the treatment of sensory neuropathy induced by a marine neurotoxic poisoning

Applicants:

Universite DE Bretagne Occidentale, Brest, FR;

Centre Hospitalier Regional ET Universitaire DE Brest, Brest, FR;

Inserm (Institut National DE LA Sante ET DE LA Recherche Medicale), Paris, FR;

Inventors:

Raphaele Le Garrec, Landunvez, FR;

Killian L'Herondelle, Brest, FR;

Laurent Misery, Plougastel, FR;

Ophelie Pierre, Thiais, FR;

Olivier Mignen, Logonna Daoulas, FR;

Assignees:

Universite De Bretagne Occidentale, Brest, FR;

Centre Hospitalier Regional Et Universitaire De Brest, Brest, FR;

INSERM (Institut National de la Santé et de la Recherche Médicale), Paris, FR;

Attorneys:

Morse, Barnes-Brown & Pendleton, P.C.

Martin Z. Zhang

Russell L. Widom

Primary Examiner:

Lianko G Garyu

Assistant Examiner:

Kristina M Hellman

Int. Cl.
CPC ...
A61K 31/454 (2006.01); A61K 31/438 (2006.01); A61K 38/05 (2006.01); A61K 39/395 (2006.01); A61K 45/00 (2006.01); A61P 25/02 (2006.01); C12N 5/071 (2010.01); C12N 5/0793 (2010.01); G01N 33/50 (2006.01);
U.S. Cl.
CPC ...
A61K 31/438 (2013.01); A61K 38/05 (2013.01); A61P 25/02 (2018.01); C12N 5/062 (2013.01); C12N 5/0629 (2013.01); G01N 33/5023 (2013.01); C12N 2501/11 (2013.01); C12N 2501/13 (2013.01); C12N 2501/33 (2013.01); C12N 2501/999 (2013.01); C12N 2502/083 (2013.01); C12N 2502/094 (2013.01);
Abstract

The present invention relates to the treatment of sensory neuropathy induced by a marine neurotoxic poisoning. The invention further encompasses an in vitro method for producing a neuro-cutaneous model allowing to study the cellular and/or molecular mechanisms involved in said neuropathy, a neuro-cutaneous model obtainable according to said method, and applications thereof.

Find Patent Forward Citations

Le Garrec, Raphaele. (2025). Protease-activated receptor-2 inhibitors for the treatment of sensory neuropathy induced by a marine neurotoxic poisoning (U.S. Patent No. 12350260). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12350260

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