The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 01, 2025
Filed:
Aug. 22, 2019
Denka Company Limited, Tokyo, JP;
National University Corporation Hokkaido University, Sapporo, JP;
Kazuhiro Nouso, Okayama, JP;
Kazuhiro Nouso, Okayama, JP;
Yasuki Ito, Gosen, JP;
Motoko Ohta, Gosen, JP;
Hitoshi Chiba, Sapporo, JP;
Toshihiro Sakurai, Sapporo, JP;
Hiroyuki Okada, Okayama, JP;
DENKA COMPANY LIMITED, Tokyo, JP;
NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY, Sapporo, JP;
KAZUHIRO NOUSO, Okayama, JP;
Abstract
Provided are a method of assisting the detection of nonalcoholic steatohepatitis (NASH) and a method that is able to assist in determining the degree of progression of any condition associated with NASH, which are far less invasive than liver biopsy and include simple operations and are independent of the skills of technicians. The present invention provides a method of assisting the detection of nonalcoholic steatohepatitis, including measuring the abundance of LDL-TG and/or ApoE-rich HDL-C contained in a test blood sample isolated from a living body. Also, the present invention provides a method of assisting in determining the degree of progression of at least one medical condition associated with nonalcoholic steatohepatitis, which medical condition(s) is(are) selected from the group consisting of fatty degeneration (steatosis), inflammation, ballooning degeneration, and fibrosis, including measuring the abundance of LDL-TG and/or ApoE-rich HDL-C contained in a test blood sample isolated from a living body.