The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 01, 2025
Filed:
Apr. 27, 2021
Bruker Cellular Analysis, Inc., Emeryville, CA (US);
Yelena Bronevetsky, Emeryville, CA (US);
Annamaria Mocciaro, Emeryville, CA (US);
Guido K. Stadler, Emeryville, CA (US);
Peter J. Beemiller, Emeryville, CA (US);
Natalie C. Marks, Emeryville, CA (US);
Duane Smith, Emeryville, CA (US);
Vincent Haw Tien Pai, Emeryville, CA (US);
Jason M. McEwen, Emeryville, CA (US);
Amanda L. Goodsell, Emeryville, CA (US);
John A. Tenney, Emeryville, CA (US);
Thomas M. Vetterli, Emeryville, CA (US);
Hansohl E. Kim, Emeryville, CA (US);
BRUKER CELLULAR ANALYSIC, INC., Emeryville, CA (US);
Abstract
Methods are provided for the assay of secreted biomolecules using automated detection and characterization of micro-objects in a microfluidic device. The biomolecules can be secreted by cells, particularly immunological cells, such as T cells. The biomolecules being assayed can include cytokines, growth factors, and the like. Methods are also provided for assaying the cytotoxicity of a cell with respect to another, target cell. Also provided are kits and non-transitory computer-readable media in which programs are stored for causing a system comprising a computer to perform automated methods for detecting secreted biomolecules and/or cytotoxicity in a microfluidic device.