The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 01, 2025

Filed:

Apr. 10, 2023
Applicant:

Quidel Corporation, San Diego, CA (US);

Inventors:

Irene Sinn Blandy, San Diego, CA (US);

Rayna Thiesen, San Diego, CA (US);

Scott Alexander Fall, San Diego, CA (US);

Robert Reed, Carlsbad, CA (US);

Robert Weiller, Encinitas, CA (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/50 (2006.01); B01D 15/00 (2006.01); B01L 3/00 (2006.01); G01N 33/49 (2006.01);
U.S. Cl.
CPC ...
G01N 33/5002 (2013.01); B01L 3/502 (2013.01); B01L 3/5082 (2013.01); G01N 33/491 (2013.01); B01D 15/00 (2013.01); B01D 2221/10 (2013.01); B01D 2239/0407 (2013.01); B01L 2200/0689 (2013.01); B01L 2300/047 (2013.01); B01L 2300/0681 (2013.01); B01L 2300/0832 (2013.01); B01L 2300/0838 (2013.01); B01L 2300/123 (2013.01); B01L 2300/161 (2013.01); B01L 2400/0406 (2013.01); B01L 2400/0481 (2013.01); B01L 2400/0683 (2013.01);
Abstract

Separation of the cellular components of whole blood, or other biological fluid, from plasma or serum can be achieved for assay analysis. A device for facilitating separation can include, for example, a capillary tube that accurately draws target blood volume, a pad that chemically interacts with red-blood cells, such that the red blood cells become chemically and/or physically trapped within pad material, a mechanism for plasma recovery from the pad upon diffusion or active mixing, and a dropper tip that facilitates dispensing the mixture onto a test device. The treatment of the cellular components can be performed prior to contact with a buffer solution, so release of the cellular components into the buffer solution is reduced or prevented. Additional filtration can be provided to filter any remaining cellular components in the mixture.


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