The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 01, 2025
Filed:
Jun. 14, 2018
Applicant:
Technion Research & Development Foundation Limited, Haifa, IL;
Inventors:
Amit Meller, Haifa, IL;
Michelle Patkin, Haifa, IL;
Tal Gilboa, Haifa, IL;
Yana Ben Zvi Rozevsky, Kiryat Motzkin, IL;
Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6816 (2018.01); C12Q 1/6827 (2018.01); G01N 33/487 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6816 (2013.01); C12Q 1/6827 (2013.01); G01N 33/48721 (2013.01); C12Q 2521/501 (2013.01); C12Q 2563/179 (2013.01); C12Q 2565/631 (2013.01);
Abstract
The present invention concerns compositions, kits and methods for genetic variation detection and classification. These methods combine the specificity of a ligation reaction with the single-molecule sensitivity of nanopore biosensors. This invention can achieve clinical detection of many diseases, including bacterial infections and cancer entities, by identification of specific genetic alterations.