The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 01, 2025
Filed:
Aug. 31, 2019
Applicant:
Yale University, New Haven, CT (US);
Inventors:
Paul Stabach, Woodbridge, CT (US);
Demetrios Braddock, Guilford, CT (US);
Assignee:
YALE UNIVERSITY, New Haven, CT (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 9/14 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C12N 9/14 (2013.01); A61K 38/00 (2013.01); C07K 2319/02 (2013.01); C07K 2319/30 (2013.01); C12Y 306/01009 (2013.01);
Abstract
The present invention includes ENPP1 polypeptides with improved in vivo half-lives. The invention further provides an ENPP1 polypeptide fusion comprising an ENPP1 polypeptide fused to a Fc region of an immunoglobulin, wherein the polypeptide fusion comprises at least one point mutation.