The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 01, 2025

Filed:

Nov. 03, 2020
Applicant:

Korea Research Institute of Bioscience and Biotechnology, Daejeon, KR;

Inventors:

Mi Young Son, Daejeon, KR;

Ohman Kwon, Daejeon, KR;

Kwang Bo Jung, Daejeon, KR;

Kyeong-Ryoon Lee, Daejeon, KR;

Cho Rok Jung, Daejeon, KR;

Janghwan Kim, Daejeon, KR;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 5/071 (2010.01); A61K 35/38 (2015.01); G01N 33/50 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0679 (2013.01); A61K 35/38 (2013.01); G01N 33/5044 (2013.01); C12N 2501/11 (2013.01); C12N 2501/16 (2013.01); C12N 2501/33 (2013.01); C12N 2501/415 (2013.01); C12N 2501/42 (2013.01); C12N 2506/23 (2013.01); C12N 2506/45 (2013.01);
Abstract

The present invention relates to a method for preparing a human intestinal epithelial model. The human intestinal epithelial model, prepared by the method according to the present invention, has all characteristics of goblet cells, enteroendocrine cells, and Paneth cells, and thus can highly mimic the function of actual human intestinal cells, so that the human intestinal epithelial model can be effectively used for development of new drugs, evaluation of drug absorption and toxicity, or evaluation of engraftment of intestinal microorganisms, or as a composition for in vivo transplantation.


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