The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 01, 2025
Filed:
Jun. 05, 2020
University of Kentucky Research Foundation, Lexington, KY (US);
R.j. Reynolds Tobacco Company, Winston-Salem, NC (US);
Ling Yuan, Lexington, KY (US);
Sanjay K. Singh, Lexington, KY (US);
Sitakanta Pattanaik, Lexington, KY (US);
Darlene Madeline Lawson, Chapel Hill, NC (US);
University of Kentucky Research Foundation, Lexington, KY (US);
R. J. Reynolds Tobacco Company, Winston-Salem, NC (US);
Abstract
A method of decreasing conversion of nicotine to nornicotine is provided herein. The methods includes administering at least one basic region/leucine zipper (bZIP) type transcription factor inhibitor to an organism in need thereof. Also provided herein is a method of decreasing conversion of nicotine to nornicotine including mutating a bZIP type transcription factor binding site on a promoter of a nicotine N-demethylase (NND). Further provided herein is a method of decreasing conversion of nicotine to nornicotine including mutating a plant genome to knockout at least one bZIP type transcription factor.