The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 01, 2025
Filed:
Mar. 29, 2021
Mie University, Tsu, JP;
Daiichi Sankyo Company, Limited, Tokyo, JP;
Hiroshi Shiku, Tsu, JP;
Yasushi Akahori, Tsu, JP;
Kento Tanaka, Tokyo, JP;
Ayaka Yatsu, Tokyo, JP;
Junya Ichikawa, Tokyo, JP;
Toshiaki Ohtsuka, Tokyo, JP;
Shiho Kozuma, Tokyo, JP;
Ryuji Hashimoto, Tokyo, JP;
Makiko Nakayama, Tokyo, JP;
Naoya Shinozaki, Tokyo, JP;
Kensuke Nakamura, Tokyo, JP;
Ichiro Watanabe, Tokyo, JP;
Shinji Furuzono, Tokyo, JP;
MIE UNIVERSITY, Tsu, JP;
DAIICHI SANKYO COMPANY, LIMITED, Tokyo, JP;
Abstract
An antibody that can be used as an anti-tumor agent and an anti-tumor agent comprises a molecule containing such an antibody. Such an antibody or a binding fragment thereof comprises: a heavy chain CDRH1 consisting of SEQ ID NO: 54, a heavy chain CDRH2 consisting of SEQ ID NO: 55, a heavy chain CDRH3 consisting of SEQ ID NO: 56, a light chain CDRL1 consisting of SEQ ID NO: 57 or a light chain CDRL1 consisting of an amino acid sequence derived from SEQ ID NO: 57 in which amino acid 7 is W and/or amino acid 8 is K, a light chain CDRL2 consisting of SEQ ID NO: 58, and a light chain CDRL3 consisting of SEQ ID NO: 59 or a light chain CDRL3 consisting of an amino acid sequence derived from SEQ ID NO: 59 in which amino acid 2 is A or S.