logo

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12344672 B1

PDFFull Text
Date of Patent:
Jul. 01, 2025

Filed:

Jul. 12, 2019

Antibody molecules that bind pd-l1 and cd137

Applicant:

Invox Pharma Limited, London, GB;

Inventors:

Matthew Lakins, Cambridge, GB;

Jose Munoz-Olaya, Cambridge, GB;

Francisca Wollerton, Cambridge, GB;

Sarah Batey, Cambridge, GB;

Mihriban Tuna, Cambridge, GB;

Alexander Koers, Cambridge, GB;

Assignee:

INVOX PHARMA LIMITED, London, GB;

Attorney:

Wolf, Greenfield & Sacks, P.C.

Primary Examiner:

Daniel E Kolker

Assistant Examiner:

Brianna K Swartwout

Int. Cl.
CPC ...
C07K 16/28 (2006.01); A61K 39/00 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2878 (2013.01); A61P 35/00 (2018.01); C07K 16/2827 (2013.01); A61K 2039/507 (2013.01); A61K 2039/545 (2013.01); C07K 2317/24 (2013.01); C07K 2317/31 (2013.01); C07K 2317/33 (2013.01); C07K 2317/34 (2013.01); C07K 2317/526 (2013.01); C07K 2317/60 (2013.01); C07K 2317/75 (2013.01); C07K 2317/92 (2013.01); C07K 2317/94 (2013.01);
Abstract

The present application relates to antibody molecules that bind both PD-L1 and CD 137 and are able to induce agonism of CD137. The antibody molecules comprise a CDR-based binding site for PD-L1, and a CD137 antigen-binding site that is located in a constant domain of the antibody molecule. The antibody molecules of the invention find application, for example, in the treatment of diseases, such as cancer.

Find Patent Forward Citations

Quick Actions:

Lakins, Matthew. (2025). Antibody molecules that bind pd-l1 and cd137 (U.S. Patent No. 12344672). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12344672

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

Loading…