The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 01, 2025
Filed:
Apr. 23, 2019
Applicant:
National Research Council of Canada, Ottawa, CA;
Inventors:
Hung Fang, Ottawa, CA;
Danica Stanimirovic, Ottawa, CA;
Arsalan Haqqani, Kanata, CA;
Will Costain, Ottawa, CA;
Gregory Hussack, Ottawa, CA;
Assignee:
National Research Council of Canada, Ottawa, CA;
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 47/68 (2017.01); A61P 21/00 (2006.01); C07K 14/765 (2006.01); C07K 16/28 (2006.01); A61K 9/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2863 (2013.01); A61K 47/6843 (2017.08); A61P 21/00 (2018.01); C07K 14/765 (2013.01); A61K 9/0019 (2013.01); A61K 2039/505 (2013.01);
Abstract
The present invention relates to a compound comprising an antibody or a fragment thereof operable to transmigrate across the blood-brain barrier (BBB), and a polypeptide related to the treatment of lysosomal storage disease (LSD), for the treatment of α-synucleinopathies, or both. The present invention also relates to pharmaceutical compositions and methods for 5 treating LSDs, treating, α-synucleinopathies, or both.