The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 01, 2025

Filed:

Mar. 27, 2020
Applicants:

Medigene Immunotherapies Gmbh, Planegg-Martinsried, DE;

Regeneron Pharmaceuticals, Inc., Tarrytown, NY (US);

Inventors:

Christian Ellinger, Munich, DE;

Daniel Sommermeyer, Munich, DE;

Geoffrey Parsons, Jamaica Plain, MA (US);

Jasdeep Mann, Lake Forest Park, WA (US);

Assignees:

MEDIGENE IMMUNOTHERAPIES GMBH, Planegg-Martinsried, DE;

Regeneron Pharmaceuticals, Inc., Tarrytown, NY (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/02 (2006.01); A61K 35/17 (2015.01); A61P 35/00 (2006.01); C07K 14/725 (2006.01); C12N 5/0783 (2010.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/7051 (2013.01); A61K 35/17 (2013.01); A61P 35/00 (2018.01); C12N 5/0636 (2013.01); A61K 38/00 (2013.01); C07K 2319/00 (2013.01);
Abstract

The present invention relates to an isolated T cell receptor (TCR) specific for MAGE-A4 and a polypeptide comprising a functional portion of the TCR. Further implicated are a multivalent TCR complex, a nucleic acid encoding a TCR, a cell expressing the TCR and a pharmaceutical composition comprising the TCR. The invention also refers to the TCR for use as a medicament, in particular to the TCR for use in the treatment of cancer.


Find Patent Forward Citations

Loading…