The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 01, 2025
Filed:
Dec. 13, 2018
Applicant:
Bang Ding, Shanghai, CN;
Inventors:
Zeling Cai, Shanghai, CN;
Yi Chen, Shanghai, CN;
Assignee:
[object Object];
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 14/525 (2006.01); A61K 31/45 (2006.01); A61K 31/704 (2006.01); A61K 38/12 (2006.01); A61K 38/19 (2006.01); A61K 39/00 (2006.01); A61K 39/395 (2006.01); A61K 45/06 (2006.01); A61P 35/00 (2006.01); C07K 16/28 (2006.01); C07K 16/32 (2006.01);
U.S. Cl.
CPC ...
C07K 14/525 (2013.01); A61K 31/45 (2013.01); A61K 31/704 (2013.01); A61K 38/12 (2013.01); A61K 38/191 (2013.01); A61K 39/3955 (2013.01); A61K 39/39558 (2013.01); A61K 45/06 (2013.01); A61P 35/00 (2018.01); C07K 16/2863 (2013.01); C07K 16/32 (2013.01); A61K 2039/505 (2013.01); C07K 2317/14 (2013.01); C07K 2317/24 (2013.01); C07K 2317/73 (2013.01); C07K 2319/02 (2013.01); C07K 2319/30 (2013.01);
Abstract
Provided is an antibody-tumor necrosis factor α fusion protein and its preparation and applications. Specifically, the present disclosure relates to a fusion protein comprising an antibody moiety and a TNFα moiety, a nucleic acid molecule encoding same, a nucleic acid construct, a host cell and a method of production thereof, as well as applications of these materials in prevention and/or treatment of tumors.