The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 01, 2025

Filed:

Mar. 29, 2018
Applicant:

Polaris Group, Grand Cayman, Grand Cayman, KY;

Inventors:

Robert J. Almassy, Vista, CA (US);

Elena Brin, San Diego, CA (US);

Richard E. Showalter, El Cajon, CA (US);

James A. Thomson, San Diego, CA (US);

Assignee:

POLARIS GROUP, Grand Cayman, KY;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 14/525 (2006.01); A61K 38/17 (2006.01); A61K 38/50 (2006.01); A61K 47/60 (2017.01); A61K 47/64 (2017.01); A61K 47/68 (2017.01); A61P 35/00 (2006.01); C07K 14/705 (2006.01); C12N 9/78 (2006.01);
U.S. Cl.
CPC ...
C07K 14/525 (2013.01); A61K 38/1761 (2013.01); A61K 38/50 (2013.01); A61K 47/60 (2017.08); A61K 47/642 (2017.08); A61K 47/6815 (2017.08); A61P 35/00 (2018.01); C07K 14/70575 (2013.01); C12N 9/78 (2013.01); C12Y 305/03006 (2013.01);
Abstract

Provided are conjugates of an arginine deiminase (ADI) and a Tumor Necrosis Factor (TNF) superfamily ligand, and related compositions and methods of use thereof. Also provided are conjugates of a hexameric polypeptide and a trimeric polypeptide, conjugates of a first and second trimeric polypeptide, and related compositions and methods of use thereof.


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