The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 01, 2025

Filed:

Mar. 24, 2021
Applicants:

The Medical College of Wisconsin, Inc., Milwaukee, WI (US);

Wisconsin Alumni Research Foundation, Madison, WI (US);

Inventors:

Joseph T. Barbieri, New Berlin, WI (US);

Amanda Przedpelski, Milwaukee, WI (US);

Eric A. Johnson, Madison, WI (US);

Sabine Pellett, Madison, WI (US);

William H. Tepp, Stoughton, WI (US);

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 39/08 (2006.01); A61K 39/215 (2006.01); A61K 47/55 (2017.01); C07K 14/005 (2006.01); C07K 14/33 (2006.01);
U.S. Cl.
CPC ...
C07K 14/005 (2013.01); A61K 39/08 (2013.01); A61K 39/215 (2013.01); C07K 14/33 (2013.01);
Abstract

Provided herein are antigenic peptides comprising the SARS-COV-2 spike protein receptor binding domain (CRBD) polypeptide or portions thereof, linked to a non-catalytic, non-toxic tetanus toxin variant (i.e., a modified tetanus toxin or 'MTT') and vaccine compositions comprising the same. In addition, provided herein are methods for making and using CRBD-MTT fusion proteins as immunogenic agents.


Find Patent Forward Citations

Loading…