The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 01, 2025

Filed:

Jul. 20, 2020
Applicant:

Reata Pharmaceuticals, Inc., Irving, TX (US);

Inventors:

Xin Jiang, Coppell, TX (US);

Christopher F. Bender, Garland, TX (US);

Ha Do, Irving, TX (US);

Haizhou Sun, Irving, TX (US);

Melean Visnick, Irving, TX (US);

Assignee:

REATA PHARMACEUTICALS, INC., Irving, TX (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/14 (2006.01); A61K 9/19 (2006.01); C07J 53/00 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
C07J 53/002 (2013.01); A61K 9/0014 (2013.01); A61K 9/0019 (2013.01); A61K 9/0053 (2013.01);
Abstract

Disclosed herein are compounds of the formula: wherein the variables are defined herein. Also provided are pharmaceutical compositions thereof. In some aspects, the compounds and compositions provided herein may be used as antioxidant inflammation modulators. In some aspects, the present disclosure provides methods wherein the compounds and composition described herein are used for the treatment of diseases and disorders, including those associated with inflammation and cancer.


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