The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 01, 2025

Filed:

Oct. 21, 2020
Applicant:

Broadenbio Co., Ltd., Beijing, CN;

Inventors:

Qi Wang, Beijing, CN;

Gongping Duan, Beijing, CN;

Wei Hua, Beijing, CN;

Xingmin Zhang, Beijing, CN;

Assignee:

BroadenBio Co., Ltd., Beijing, CN;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 471/18 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
C07D 471/18 (2013.01); A61P 35/00 (2018.01);
Abstract

Provided are a compound of formula (I), or a pharmaceutically acceptable salt, solvate, active metabolite, polymorph, isotopic label, isomer or prodrug thereof, and a use thereof. The above-mentioned compound has a very strong inhibitory effect on the FGFR4 kinase activity and the proliferative activity of Hep 3B cells with high FGFR4 expression.


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