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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12343721 B1

PDFFull Text
Date of Patent:
Jul. 01, 2025

Filed:

Oct. 14, 2016

Microfluidic chip, microfluidic device, associated uses and methods

Applicants:

Universidad DE Zaragoza, Saragossa, ES;

Instituto Tecnológico DE Aragón, Saragossa, ES;

Centro DE Investigación Biomédica En Red, Madrid, ES;

Inventors:

Luis José Fernández Ledesma, Saragossa, ES;

Rosa Maria Monge Prieto, Saragossa, ES;

Jose Luis Calavia Calvo, Saragossa, ES;

Jorge Santolaria Mazo, Saragossa, ES;

Javier Orús Pontaque, Saragossa, ES;

Carlos Peribáñez Subirón, Saragossa, ES;

José Manuel Rodriguez Fortún, Saragossa, ES;

Ignacio Ochoa Garrido, Madrid, ES;

Assignees:

UNIVERSIDAD DE ZARAGOZA, Saragossa, ES;

INSTITUTO TECNOLÓGICO DE ARAGÓN, Saragossa, ES;

CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED, Madrid, ES;

Attorney:

ArentFox Schiff LLP

Primary Examiner:

Jennifer Wecker

Assistant Examiner:

Steven Ray Castaneda

Int. Cl.
CPC ...
B01L 3/00 (2006.01); B01L 9/00 (2006.01); B32B 3/30 (2006.01); B32B 25/08 (2006.01); B32B 37/16 (2006.01); B32B 37/18 (2006.01); B32B 38/00 (2006.01); F16K 99/00 (2006.01);
U.S. Cl.
CPC ...
B01L 3/502707 (2013.01); B01L 3/00 (2013.01); B01L 3/502715 (2013.01); B01L 3/502738 (2013.01); B01L 9/50 (2013.01); B32B 3/30 (2013.01); B32B 25/08 (2013.01); B32B 37/16 (2013.01); B32B 37/182 (2013.01); B32B 38/0008 (2013.01); F16K 99/0015 (2013.01); F16K 99/0048 (2013.01); B01L 2200/027 (2013.01); B01L 2200/0689 (2013.01); B01L 2200/12 (2013.01); B01L 2300/043 (2013.01); B01L 2300/123 (2013.01); B01L 2400/0484 (2013.01); B01L 2400/06 (2013.01); B01L 2400/0638 (2013.01); B01L 2400/0655 (2013.01); F16K 2099/0084 (2013.01);
Abstract

The present invention relates to a chip equipped with a plurality of compact microfluidic valves with multiple inlets and outlets, actuated by means of a flexible membrane system. The chip preferably comprises a deformable sealing layer made of at least one flexible, elastic, and insulating material; a structure formed by a succession of one or several microstructured layers, wherein said structure comprises one or several micro-chambers, one or several microfluidic channels, and one or several fluidic inlets and outlets; and wherein said structure is installed on a base substrate. The invention likewise relates to a microfluidic device that comprises the aforementioned chip, to a method for the fabrication of the chip, and to the uses associated with the chip and the microfluidic device.

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