The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 01, 2025

Filed:

Mar. 18, 2022
Applicant:

Osiris Therapeutics, Inc., Columbia, MD (US);

Inventors:

Thomas E. Uveges, Elkridge, MD (US);

Jin-Qiang Kuang, Glenelg, MD (US);

Alla Danilkovitch, Columbia, MD (US);

S. Michael Sinclair, Ellicott City, MD (US);

Sandra D. Geraghty, Elkridge, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/18 (2006.01); A61L 27/36 (2006.01); A61L 27/38 (2006.01); A61L 27/40 (2006.01); A61L 27/54 (2006.01); A61P 19/08 (2006.01);
U.S. Cl.
CPC ...
A61L 27/3608 (2013.01); A61K 38/18 (2013.01); A61K 38/1825 (2013.01); A61K 38/1841 (2013.01); A61K 38/1866 (2013.01); A61L 27/3604 (2013.01); A61L 27/365 (2013.01); A61L 27/3683 (2013.01); A61L 27/3687 (2013.01); A61L 27/3691 (2013.01); A61L 27/3821 (2013.01); A61L 27/3834 (2013.01); A61L 27/3847 (2013.01); A61L 27/40 (2013.01); A61L 27/54 (2013.01); A61P 19/08 (2018.01); A61L 2300/414 (2013.01); A61L 2300/64 (2013.01); A61L 2430/02 (2013.01); A61L 2430/40 (2013.01);
Abstract

Provided herein is a bone repair composition that is composed of periosteum containing an angiogenic growth factor(s), cancellous bone chips containing viable osteogenic cells, and, optionally, demineralized bone matrix (DBM) chips. Also provided herein are articles of manufacture and methods of use thereof to treat bone defects.


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