The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 01, 2025
Filed:
Feb. 17, 2018
Applicant:
Purdue Research Foundation, West Lafayette, IN (US);
Inventors:
Philip S. Low, West Lafayette, IN (US);
Madduri Srinivasarao, West Lafayette, IN (US);
Boning Zhang, West Lafayette, IN (US);
Assignee:
Purdue Research Foundation, West Lafayette, IN (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/66 (2017.01); A61K 40/10 (2025.01); A61K 40/11 (2025.01); A61K 40/31 (2025.01); A61K 40/42 (2025.01); A61K 47/69 (2017.01); C07K 14/725 (2006.01); C12N 9/90 (2006.01); C12N 15/62 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
A61K 47/66 (2017.08); A61K 40/10 (2025.01); A61K 40/11 (2025.01); A61K 40/31 (2025.01); A61K 40/4211 (2025.01); A61K 47/6901 (2017.08); C07K 14/7051 (2013.01); C12N 9/90 (2013.01); C12N 15/62 (2013.01); A61K 38/00 (2013.01); A61K 2239/31 (2023.05); A61K 2239/38 (2023.05); A61K 2239/48 (2023.05); C07K 2319/03 (2013.01); C07K 2319/20 (2013.01); C07K 2319/912 (2013.01); C12Y 502/01008 (2013.01);
Abstract
A drug delivery platform providing flexible fine tune of cell therapy is disclosed herein. Particularly, an engineered fusion protein is coupled with a high affinity ligand carrying at least one payload of drug to be internalized by the transplanted cell to observe or regulate transplanted cell therapy effects.