The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 01, 2025

Filed:

Jul. 10, 2020
Applicant:

Novo Nordisk A/s, Bagsvaerd, DK;

Inventors:

Jeppe Sturis, Vaerloese, DK;

Svend Havelund, Bagsvaerd, DK;

Karen-Margrethe Pedersen, Copenhagen V, DK;

Assignee:

Novo Nordisk A/S, Bagsvaerd, DK;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); A61K 9/00 (2006.01); A61K 31/7084 (2006.01); A61K 33/30 (2006.01); A61K 38/28 (2006.01); A61K 47/02 (2006.01); A61K 47/18 (2017.01); A61P 3/10 (2006.01);
U.S. Cl.
CPC ...
A61K 38/28 (2013.01); A61K 9/0019 (2013.01); A61K 31/7084 (2013.01); A61K 33/30 (2013.01); A61K 47/02 (2013.01); A61K 47/18 (2013.01); A61P 3/10 (2018.01);
Abstract

The invention concerns a soluble insulin preparation comprising NϵB29-hexadecandioyl-γ-Glu-(desB30) human insulin in a concentration from 1800 nmol/ml to 4200 nmol/ml, Zinc ions in a concentration from 4.0 Zn/6Ins to 7.0 Zn/6Ins, Niacinamide in a concentration from 110 mM to 220 mM or treprostinil in a concentration from 0.02 μg/ml to 1 μg/ml, Citrate in a concentration from 6 mM to 40 mM, and pH in the range from 7.0 to 8.0. The invention further comprises a method for using the soluble insulin preparation for reducing the blood glucose level in a mammal and a process for preparing the soluble insulin preparations.


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