The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 01, 2025
Filed:
Nov. 04, 2019
Applicant:
Iovance Biotherapeutics, Inc., San Carlos, CA (US);
Inventors:
Cecile Chartier-Courtaud, Palo Alto, CA (US);
Maria Fardis, San Carlos, CA (US);
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/17 (2025.01); A61K 38/20 (2006.01); A61K 39/395 (2006.01); A61K 40/11 (2025.01); A61K 40/42 (2025.01); C12N 5/0783 (2010.01);
U.S. Cl.
CPC ...
A61K 38/2013 (2013.01); A61K 39/3955 (2013.01); A61K 40/11 (2025.01); A61K 40/42 (2025.01); C12N 5/0638 (2013.01); C12N 2501/2302 (2013.01); C12N 2501/2315 (2013.01); C12N 2501/2321 (2013.01); C12N 2501/515 (2013.01); C12N 2501/727 (2013.01); C12N 2501/999 (2013.01); C12N 2502/11 (2013.01);
Abstract
In some embodiments, methods of expanding tumor infiltrating lymphocytes using AKT pathway inhibitors and methods of using the expanded tumor infiltrating lymphocytes in the treatment of human diseases, including cancers, are disclosed.