The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 01, 2025
Filed:
May. 18, 2020
Applicant:
Dignity Health, San Francisco, CA (US);
Inventor:
Zaman Mirzadeh, Phoenix, AZ (US);
Assignee:
DIGNITY HEALTH, San Francisco, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/39 (2015.01); A61K 9/00 (2006.01); A61K 9/08 (2006.01); A61K 35/30 (2015.01); A61P 3/10 (2006.01);
U.S. Cl.
CPC ...
A61K 35/30 (2013.01); A61K 9/0085 (2013.01); A61K 9/08 (2013.01); A61P 3/10 (2018.01);
Abstract
Disclosed herein are compositions, methods of treatment, and uses of inhibitory interneuron precursors, derived from the brain's medial ganglionic eminence, or differentiated from iPSC or ESCs, for the treatment of pre-diabetes or diabetes. In some embodiments, compositions including inhibitory interneuron precursors are transplanted into the arcuate nucleus of the hypothalamus region of the brain, to treat, for example, diabetes, such as, type-2 diabetes, In further embodiments, inhibitory interneuron precursors are used in the manufacture of a medicament for the treatment of diabetes, for example, type-2 diabetes.