The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 01, 2025
Filed:
Mar. 27, 2023
Applicant:
Rutgers, the State University of New Jersey, New Brunswick, NJ (US);
Inventors:
Debra L. Laskin, Basking Ridge, NJ (US);
Jaclynn A. Meshanni, Hawthorne, NJ (US);
Grace L. Guo, Bridgewater, NJ (US);
Andrew J. Gow, Princeton, NJ (US);
Jeffrey D. Laskin, Piscataway, NJ (US);
Assignee:
RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY, New Brunswick, NJ (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/575 (2006.01); A61P 11/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/575 (2013.01); A61P 11/00 (2018.01);
Abstract
A method of treating reduced pulmonary function by administering an effective dose of a Farnesoid X Receptor (FXR) agonist, particularly obeticholic acid, is disclosed. Also disclosed is an in vivo animal model of lung injury and altered functioning, useful for identifying compounds active in restoring pulmonary function.