logo

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12338293 B1

PDFFull Text
Date of Patent:
Jun. 24, 2025

Filed:

Mar. 23, 2022

Upar antibodies and fusion proteins with the same

Applicant:

Mural Oncology, Inc., Woburn, MA (US);

Inventors:

Jijun Dong, Weston, MA (US);

Pinar Gurel, Cambridge, MA (US);

Joshua Heiber, Watertown, MA (US);

Yuan Hu, Belmont, MA (US);

Assignee:

Mural Oncology, Inc., Waltham, MA (US);

Attorney:

Fish & Richardson P.C.

Primary Examiner:

Jeffrey Stucker

Assistant Examiner:

Brittney E Donoghue

Int. Cl.
CPC ...
C07K 16/28 (2006.01); A61K 38/00 (2006.01); A61K 39/00 (2006.01); A61P 35/00 (2006.01); C07K 14/54 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2896 (2013.01); A61P 35/00 (2018.01); C07K 14/5434 (2013.01); A61K 38/00 (2013.01); A61K 2039/505 (2013.01); A61K 2039/54 (2013.01); A61K 2039/545 (2013.01); C07K 2317/24 (2013.01); C07K 2317/55 (2013.01); C07K 2317/565 (2013.01); C07K 2317/622 (2013.01); C07K 2317/92 (2013.01); C07K 2319/30 (2013.01);
Abstract

The disclosure provides urokinase plasminogen activator receptor (uPAR) binding polypeptides (e.g., uPAR antigen binding proteins), and fusion proteins comprising said uPAR binding polypeptides and a cytokine or variant thereof. The disclosure further provides pharmaceutical compositions comprising the uPAR binding polypeptides and fusion proteins of the disclosure and methods of treating cancer with the same. The disclosure further provides engineered IL-12 p35 and p40 polypeptides.

Find Patent Forward Citations

Dong, Jijun. (2025). Upar antibodies and fusion proteins with the same (U.S. Patent No. 12338293). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12338293

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

Loading…