The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 24, 2025
Filed:
Sep. 17, 2021
Igi Therapeutics SA, La Chaux-de-Fonds, CH;
Laure Bouchez, La Chaux-de-Fonds, CH;
Blandine Pouleau, La Chaux-de-Fonds, CH;
Marie-Agnes Doucey, La Chaux-de-Fonds, CH;
Elie Dheilly, La Chaux-de-Fonds, CH;
Stanislas Blein, La Chaux-de-Fonds, CH;
Cian Stutz, La Chaux-de-Fonds, CH;
Carole Estoppey, La Chaux-de-Fonds, CH;
Jeremy Loyau, La Chaux-de-Fonds, CH;
Thierry Monney, La Chaux-de-Fonds, CH;
Camille Grandclement, La Chaux-de-Fonds, CH;
Stefano Sammicheli, La Chaux-de-Fonds, CH;
IGI Therapeutics SA, La Chaux-de-Fonds, CH;
Abstract
Novel bispecific heterodimeric immunoglobulins that target both a component of the human CD47 antigen and human CD38 antigen are provided and in particular those comprising an anti-CD38 heavy chain variable region and a light chain variable region and an anti-CD47 heavy chain variable region and a light chain variable region. The present invention also relates to the use of this novel class of bispecific heterodimeric immunoglobulins to treat autoimmune and proliferative diseases and in particular cancers such as hematologic malignancies and solid tumors.