The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 24, 2025
Filed:
May. 15, 2020
The Broad Institute, Inc., Cambridge, MA (US);
Bayer Aktiengesellschaft, Leverkusen, DE;
Kai Thede, Leverkusen, DE;
Sven Wittrock, Leverkusen, DE;
Anne Mengel, Leverkusen, DE;
David McKinney, Cambridge, MA (US);
Christopher Lemke, Cambridge, MA (US);
Steven J. Ferrara, Cambridge, MA (US);
Laura Furst, Cambridge, MA (US);
Guo Wei, Cambridge, MA (US);
Patrick R. McCarren, Cambridge, MA (US);
The Broad Institute, Inc., Cambridge, MA (US);
Bayer Aktiengesellschaft, Leverkusen, DE;
Abstract
The present invention relates to methods of preparing substituted indole derivatives of general formula (I): in which R, R, R, R, R, R, A and L are as defined herein, and intermediate compounds useful for preparing said compounds. These compounds are useful for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular of hyperproliferative disorders, as a sole agent or in combination with other active ingredients.