The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 24, 2025

Filed:

Nov. 12, 2020
Applicants:

Yuhan Corporation, Seoul, KR;

Green Cross Corporation, Yongin-si, KR;

Inventors:

Dong-Hoon Kim, Suwon-si, KR;

Jae-Eun Joo, Yongin-si, KR;

Eui-Chul Lee, Yongin-si, KR;

Tae-Dong Han, Yongin-si, KR;

Seung-Yub Shin, Osan-si, KR;

Sool-Ki Kwon, Yongin-si, KR;

Young-Gyu Kong, Yongin-si, KR;

Sang-Ho Ma, Suwon-si, KR;

Ick-Hwan Son, Yongin-si, KR;

Assignees:

Yuhan Corporation, Seoul, KR;

Green Cross Corporation, Yongin-si, KR;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 453/02 (2006.01); A61P 3/00 (2006.01); C07D 471/08 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 453/02 (2013.01); A61P 3/00 (2018.01); C07D 471/08 (2013.01); C07D 519/00 (2013.01);
Abstract

Provided are a compound having a 1,2,3,4-tetrahydronaphthalene moiety or pharmaceutically acceptable salt thereof, of Formula 1 a pharmaceutical composition comprising the same and a use thereof, where the compound having a 1,2,3,4-tetrahydronaphthalene moiety or pharmaceutically acceptable salt thereof has an inhibitory activity against glucosylceramide synthase (GCS), and therefore can be usefully applied for preventing or treating various diseases associated with GCS, such as Gaucher disease, Fabry disease, Tay-Sachs disease, Parkinson's disease, etc.


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