The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 24, 2025
Filed:
Jan. 13, 2020
Applicant:
Innate Tumor Immunity, Inc., Princeton, NJ (US);
Inventors:
Scott Hunter Watterson, Pennington, NJ (US);
Daniel O'Malley, New Hope, PA (US);
Ashvinikumar V. Gavai, Princeton Junction, NJ (US);
Patrice Gill, Levittown, PA (US);
Steven P. Seitz, Swarthmore, PA (US);
Hua Gong, King of Prussia, PA (US);
Assignee:
Innate Tumor Immunity, Inc., Princeton, NJ (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 401/10 (2006.01); A61K 31/4709 (2006.01); A61K 45/06 (2006.01); A61P 35/00 (2006.01); C07D 401/04 (2006.01); C07D 401/14 (2006.01); C07D 405/14 (2006.01); A61K 31/47 (2006.01);
U.S. Cl.
CPC ...
C07D 401/10 (2013.01); A61K 31/4709 (2013.01); A61K 45/06 (2013.01); A61P 35/00 (2018.01); C07D 401/14 (2013.01); C07D 405/14 (2013.01);
Abstract
The present invention provides compounds of Formula (I), (II) or (III): (I), (II), (III), wherein all of the variables are as defined herein. These compounds are modulators of NLRP3, which may be used as medicaments for the treatment of proliferative disorders, such as cancer in a subject (e.g., a human).