The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 24, 2025
Filed:
Jan. 22, 2021
Applicant:
Regeneron Pharmaceuticals, Inc., Tarrytown, NY (US);
Inventors:
Assignee:
REGENERON PHARMACEUTICALS, INC., Tarrytown, NY (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); A61K 39/42 (2006.01); A61K 47/22 (2006.01); A61K 47/26 (2006.01); A61P 31/12 (2006.01);
U.S. Cl.
CPC ...
A61K 39/39591 (2013.01); A61K 39/42 (2013.01); A61K 47/22 (2013.01); A61K 47/26 (2013.01); A61P 31/12 (2018.01);
Abstract
The present disclosure provides stable pharmaceutical formulations comprising a human antibody that specifically binds to Ebola Virus (EBOV). In certain embodiments, the formulations contain, in addition to an anti-EBOV antibody, a buffer, an amino acid, a non-ionic surfactant, and a stabilizer. The pharmaceutical formulations of the present disclosure exhibit a substantial degree of antibody stability upon stress, for example, agitation during transport, and storage, for example, storage at temperatures greater than 40° C.