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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12336976 B1

PDFFull Text
Date of Patent:
Jun. 24, 2025

Filed:

Sep. 06, 2023

Glutaminase inhibitor therapy

Applicant:

Board of Regents, the University of Texas System, Austin, TX (US);

Inventors:

Timothy Heffernan, Sugar Land, TX (US);

Jeffrey Kovacs, Pearland, TX (US);

Nakia Spencer, Houston, TX (US);

Christopher Bristow, Houston, TX (US);

Assignee:

Board of Regents, The University of Texas System, Austin, TX (US);

Attorneys:

Global Patent Group Inc.

Cynthia Hathaway

Michael Sertic

Primary Examiner:

Raymond J Henley, Iii

Int. Cl.
CPC ...
A61K 31/50 (2006.01); A61K 31/282 (2006.01); A61K 31/337 (2006.01); A61K 31/4196 (2006.01); A61K 31/433 (2006.01); A61K 31/501 (2006.01); A61K 31/55 (2006.01); A61K 33/243 (2019.01); A61K 45/06 (2006.01); A61P 35/00 (2006.01); G01N 33/574 (2006.01); A61K 51/04 (2006.01);
U.S. Cl.
CPC ...
A61K 31/282 (2013.01); A61K 31/337 (2013.01); A61K 31/4196 (2013.01); A61K 31/433 (2013.01); A61K 31/501 (2013.01); A61K 31/55 (2013.01); A61K 33/243 (2019.01); A61K 45/06 (2013.01); A61P 35/00 (2018.01); G01N 33/57449 (2013.01); A61K 51/0408 (2013.01);
Abstract

Disclosed herein are methods of treating a tumor or cancer in a subject whose tumor or cancer cells express low levels of asparagine synthetase (ASNS), and compounds and compositions useful in such treatment. Also disclosed herein are methods of evaluating whether to administer a compound that inhibits glutathione production or a glutaminase inhibitor to a subject with a tumor or cancer.

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Heffernan, Timothy. (2025). Glutaminase inhibitor therapy (U.S. Patent No. 12336976). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12336976

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