The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 24, 2025

Filed:

Apr. 14, 2023
Applicants:

Siemens Healthcare Gmbh, Erlangen, DE;

Stichting Radboud Universiteit, Nijmegen, NL;

Inventors:

Gabriele Bonanno, Bern, CH;

Jose Pedro Marques, Nijmegen, NL;

Tobias Kober, Lausanne, CH;

Tom Hilbert, Lausanne, CH;

Assignees:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61B 5/055 (2006.01); A61B 5/00 (2006.01); G01R 33/24 (2006.01); G01R 33/50 (2006.01); G01R 33/56 (2006.01);
U.S. Cl.
CPC ...
A61B 5/055 (2013.01); A61B 5/0042 (2013.01); G01R 33/50 (2013.01); G01R 33/5602 (2013.01); G01R 33/243 (2013.01); G01R 33/246 (2013.01);
Abstract

A qMRI system and method map qMRI parameters of a biological object. The method includes performing, by the qMRI system, N scans wherein each scan, includes: performing T2-prepared inversion pulse series, each followed by readout blocks, each magnetization preparation RF pulse series is a T2-prepared inversion pulse series containing multiple pulses and an inter-pulse duration, for varying to obtain different T2 weightings; and acquiring, by the MRI system and during each readout block of an MRI, a recovery signal generated by a part of the biological object, wherein for each readout block, an MRI signal is acquired by the MRI system at different inversion times. An image of the part is reconstructed for and from each MRI signal. A voxel-wise signal is created by concatenating intensity values for a same voxel for the reconstructed images. A physical model is fitted to the concatenated intensity values to obtain a qMRI map.


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