The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 17, 2025

Filed:

Apr. 15, 2021
Applicant:

Waters Technologies Corporation, Milford, MA (US);

Inventors:

Stephen James Shiner, Holden, MA (US);

Frank J. Marszalkowski, Jr., Milford, MA (US);

Steven M. Byrd, Ashland, MA (US);

Raymond P. Fisk, Norton, MA (US);

Mathew H. DeLano, Needham, MA (US);

Lavelay Kizekai, Coventry, RI (US);

Assignee:

Waters Technolgies Corporation, Milford, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
B01D 15/34 (2006.01); B01D 15/22 (2006.01); G01N 30/08 (2006.01); G01N 30/46 (2006.01); G01N 30/60 (2006.01);
U.S. Cl.
CPC ...
G01N 30/606 (2013.01); B01D 15/22 (2013.01); B01D 15/34 (2013.01); G01N 30/461 (2013.01); G01N 30/6065 (2013.01); G01N 2030/085 (2013.01);
Abstract

Chromatographic systems for size exclusion chromatography (SEC) are provided that comprise an inlet, an outlet, an analytic column having a first interior volume that has a first length and a first cross-sectional area normal to the first length, the first interior volume containing a first stationary phase, and a guard column having a second interior volume that has a second length and a second cross-sectional area normal to the second length, the second interior volume containing a second stationary phase. The inlet is in fluid communication with the guard column, the guard column is in fluid communication with the analytic column, and the analytic column is in fluid communication with the outlet. Moreover, the second length is smaller than the first length, and the second cross-sectional area is smaller than the first cross-sectional area.


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