The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 17, 2025
Filed:
May. 27, 2022
The General Hospital Corporation, Boston, MA (US);
Daniel Haber, Chestnut Hill, MA (US);
Shyamala Maheswaran, Lexington, MA (US);
Tanya Todorova, Malden, MA (US);
Mark Kalinich, Cambridge, MA (US);
David Tomoaki Miyamoto, Wellesley, MA (US);
Xin Hong, Malden, MA (US);
The General Hospital Corporation, Boston, MA (US);
Abstract
This disclosure relates to new assay methods for analysis of RNA, e.g., from circulating tumor cells (CTCs), tumor-specific exosomes, or tumor-specific cell-free RNA, in a subject's blood sample to determine an expression level of one or more lineage markers in the blood sample, wherein the expression level of a specific one or more lineage markers is predictive of progression-free survival and overall survival for a specific anti-cancer treatment regimen in that subject.