The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 17, 2025
Filed:
Dec. 09, 2019
Applicant:
Cambridge Enterprise Limited, Cambridge, GB;
Inventors:
Arthur Kaser, Cambridge, GB;
Mohammed Zaeem Cader, Cambridge, GB;
Assignee:
CAMBRIDGE ENTERPRISE LIMITED, Cambridge, GB;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q 1/48 (2006.01); C12Q 1/34 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/48 (2013.01); C12Q 1/34 (2013.01); G01N 2333/91142 (2013.01); G01N 2333/978 (2013.01);
Abstract
This invention relates to the finding that FAMIN (fatty acid metabolism-immunity nexus; LACC1, C13orf31)) is a trifunctional purine salvage enzyme that displays a unique combination of adenosine deaminase, purine nucleoside phosphorylase and methylthioadenosine phosphorylase activities. Methods of measuring FAMIN activity and screening for FAMIN modulators are provided that comprise determining the adenosine deaminase activity, purine nucleoside phosphorylase activity and/or methylthioadenosine phosphorylase activity of an isolated FAMIN protein.