The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 17, 2025
Filed:
Feb. 04, 2020
Applicant:
Spur Therapeutics Limited, Stevenage, GB;
Inventors:
Amit Nathwani, Rickmansworth, GB;
Jenny McIntosh, Epsom, GB;
Romuald Corbau, St Albans, GB;
Azadeh Kia, Enfield, GB;
Carlos Miranda, Watford, GB;
Assignee:
SPUR THERAPEUTICS LIMITED, Stevenage, GB;
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/24 (2006.01); A61K 38/47 (2006.01); A61P 1/16 (2006.01); C12N 15/52 (2006.01);
U.S. Cl.
CPC ...
C12N 9/2402 (2013.01); A61K 38/47 (2013.01); A61P 1/16 (2018.01); C12N 15/52 (2013.01); C12Y 302/01045 (2013.01);
Abstract
The present invention relates to polynucleotides comprising a GBA nucleotide sequence that encodes a GCase protein or fragment thereof and wherein a portion of the coding sequence is not wild type. The present invention further relates to viral particles comprising a recombinant genome comprising the polynucleotide of the invention, compositions comprising the polynucleotides or viral particles, and methods and uses of the polynucleotides, viral particles or compositions.