The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 17, 2025
Filed:
Aug. 10, 2023
Applicant:
Northeastern University, Boston, MA (US);
Inventor:
Shashi K. Murthy, Newton, MA (US);
Assignee:
Northeastern University, Boston, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
C12M 1/36 (2006.01); A61K 39/00 (2006.01); A61K 40/19 (2025.01); A61K 40/24 (2025.01); A61K 40/45 (2025.01); C12M 1/00 (2006.01); C12M 1/02 (2006.01); C12M 1/26 (2006.01); C12M 1/42 (2006.01); C12M 3/06 (2006.01); C12N 5/0784 (2010.01);
U.S. Cl.
CPC ...
C12M 41/48 (2013.01); A61K 39/0008 (2013.01); A61K 40/19 (2025.01); A61K 40/24 (2025.01); A61K 40/4524 (2025.01); C12M 23/16 (2013.01); C12M 23/28 (2013.01); C12M 27/00 (2013.01); C12M 29/04 (2013.01); C12M 33/00 (2013.01); C12M 35/08 (2013.01); C12M 41/14 (2013.01); C12N 5/0639 (2013.01); C12N 2501/22 (2013.01); C12N 2501/2306 (2013.01); C12N 2501/25 (2013.01);
Abstract
Devices, systems, and methods can be used for the automated production of dendritic cells (DC) from dendritic cell progenitors, such as monocytes obtained from peripheral blood, and the automated generation of immunotherapeutic products from those dendritic cells, all within a closed system. The invention makes it possible to obtain sufficient quantities of a subject's own DC for use in preparing and characterizing vaccines, for activating and characterizing the activation state of the subject's immune response, and to aid in preventing and/or treating cancer or infectious disease.