The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 17, 2025
Filed:
Nov. 18, 2022
Applicant:
H. Lundbeck A/s, Valby, DK;
Inventors:
Lars Christian Biilmann Rønn, Valby, DK;
Ibrahim John Malik, Valby, DK;
Jeffrey B. Stavenhagen, Valby, DK;
Søren Christensen, Valby, DK;
Jan Egebjerg, Valby, DK;
Arnout Gerritsen, Utrecht, NL;
Edward Van Den Brink, Utrecht, NL;
Paul Parren, Utrecht, NL;
Rob De Jong, Utrecht, NL;
Assignee:
H. Lundbeck A/S, Valby, DK;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/00 (2006.01); A61K 39/395 (2006.01); A61K 51/10 (2006.01); A61P 25/28 (2006.01); C07K 16/28 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/286 (2013.01); A61K 39/3955 (2013.01); A61P 25/28 (2018.01); C07K 16/28 (2013.01); A61K 2039/505 (2013.01); C07K 2317/20 (2013.01); C07K 2317/21 (2013.01); C07K 2317/24 (2013.01); C07K 2317/33 (2013.01); C07K 2317/34 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01);
Abstract
The present invention relates to monoclonal anti-Sortilin antibodies which have been found useful in correcting a deficient level of progranulin (PGRN). In particular, these antibodies can be used in the treatment of frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS).