The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 17, 2025
Filed:
Apr. 01, 2020
William Robert Arathoon Living Trust Dated August 29, 2016, Tiburon, CA (US);
William Robert Arathoon, Tiburon, CA (US);
Evan Matthew Bishop, San Jose, CA (US);
Raffaella Briante, Burlingame, CA (US);
Alissa Loren Briggs, San Jose, CA (US);
Suchismita Mohanty, Millbrae, CA (US);
Paul David Ponath, San Francisco, CA (US);
Cindy Tan, San Jose, CA (US);
Qianting Zhai, South San Francisco, CA (US);
William Robert Arathoon Living Trust Dated August 29, 2016, Tiburon, CA (US);
Abstract
Provided are multi-specific antibodies that target both a cellular efflux pump and a cancer-associated antigen as well as pharmaceutical compositions, nucleic acids, recombinant expression vectors, cells, and kits that include or encode such multi-specific antibodies. Methods of treating a subject for a cancer that include administering to the subject a multi-specific antibody that targets both a cellular efflux pump and a cancer-associated antigen are also provided. Provided as well are methods of generating the described multi-specific antibodies and reagents related thereto, including genetically modified cell lines useful in the subject methods and methods of making such genetically modified cell lines.