The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 17, 2025
Filed:
Feb. 12, 2019
Indian Institute of Technology Bombay, Mumbai, IN;
Rahul Purwar, Mumbai, IN;
Alka Dwivedi, Mumbai, IN;
Atharva Karulkar, Mumbai, IN;
Srisathya Srinivasan, Mumbai, IN;
INDIAN INSTITUTE OF TECHNOLOGY BOMBAY, Mumbai, IN;
Abstract
The present invention relates to novel humanized anti-CD19chimeric antigen receptor containing an optimized anti-CD19 binding domain effective against the treatment of disease associated with expression of the Cluster of Differentiation 19 protein (CD19), and to a nucleic acid molecule encoding the humanized CAR. The invention also encompasses a process forth preparation of the CAR, composition containing the CAR, vectors containing the polynucleotide encoding the CAR and cells expressing the Carat their surface, in particular for their use in immunotherapy.