The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 17, 2025

Filed:

Jun. 15, 2018
Applicant:

Protelica, Inc., Burlingame, CA (US);

Inventors:

Roberto Crea, Burlingame, CA (US);

Jun Yoon, Burlingame, CA (US);

Craig A. Hokanson, Pleasanton, CA (US);

Emanuela Zacco, Burlingame, CA (US);

Assignee:

PROTELICA, INC., Burlingame, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/78 (2006.01); A61K 38/00 (2006.01); A61K 40/31 (2025.01); C07K 14/705 (2006.01);
U.S. Cl.
CPC ...
C07K 14/78 (2013.01); A61K 40/31 (2025.01); C07K 14/70517 (2013.01); C07K 14/70521 (2013.01); C07K 14/70578 (2013.01); A61K 38/00 (2013.01); C07K 2317/31 (2013.01); C07K 2319/02 (2013.01); C07K 2319/03 (2013.01); C07K 2319/21 (2013.01); C07K 2319/30 (2013.01); C07K 2319/33 (2013.01); C07K 2319/70 (2013.01);
Abstract

Provided herein are chimeric antigen receptors (CARs) for binding with a target antigen, comprising at least one antigen specific targeting region comprising a fibronectin type 3 (FN3) domain polypeptide. Provided herein are multispecific chimeric antigen receptors for binding with two or more target antigens, comprising at least two antigen specific targeting regions comprising a fibronectin type 3 domain polypeptide. Also provided herein are compositions and methods of treatment relating to the use of subject CARs of the invention.


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