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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12331103 B1

PDFFull Text
Date of Patent:
Jun. 17, 2025

Filed:

Jun. 15, 2018

Fibronectin binding domain chimeric antigen receptors and methods of use thereof

Applicant:

Protelica, Inc., Burlingame, CA (US);

Inventors:

Roberto Crea, Burlingame, CA (US);

Jun Yoon, Burlingame, CA (US);

Craig A. Hokanson, Pleasanton, CA (US);

Emanuela Zacco, Burlingame, CA (US);

Assignee:

PROTELICA, INC., Burlingame, CA (US);

Attorneys:

LATHROP GPM LLP

Michael Spellberg

Primary Examiner:

Thea D'Ambrosio

Int. Cl.
CPC ...
C07K 14/78 (2006.01); A61K 38/00 (2006.01); A61K 40/31 (2025.01); C07K 14/705 (2006.01);
U.S. Cl.
CPC ...
C07K 14/78 (2013.01); A61K 40/31 (2025.01); C07K 14/70517 (2013.01); C07K 14/70521 (2013.01); C07K 14/70578 (2013.01); A61K 38/00 (2013.01); C07K 2317/31 (2013.01); C07K 2319/02 (2013.01); C07K 2319/03 (2013.01); C07K 2319/21 (2013.01); C07K 2319/30 (2013.01); C07K 2319/33 (2013.01); C07K 2319/70 (2013.01);
Abstract

Provided herein are chimeric antigen receptors (CARs) for binding with a target antigen, comprising at least one antigen specific targeting region comprising a fibronectin type 3 (FN3) domain polypeptide. Provided herein are multispecific chimeric antigen receptors for binding with two or more target antigens, comprising at least two antigen specific targeting regions comprising a fibronectin type 3 domain polypeptide. Also provided herein are compositions and methods of treatment relating to the use of subject CARs of the invention.

Find Patent Forward Citations

Crea, Roberto. (2025). Fibronectin binding domain chimeric antigen receptors and methods of use thereof (U.S. Patent No. 12331103). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12331103

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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